Plant secondary metabolites are compounds synthesized by various plants species to aid in survival in the environment. These metabolites have found a wide range of applications in nutrition, food and pharmaceutical industries due to their linkage to various health benefits. Our team develops extraction protocols and subsequent mass spectrometry analytical methods for these compounds and/or their derivatives from raw plant materials, foods, biological fluids, cells, tissues, and organs. This enables their identification, comparative profiling as well as monitoring of their distribution upon entry into the animals' or human body. Our recent focus has been in the analysis of polyphenolic compounds and hydrophobic biometabolites such as triterpenoids, Oxysterol, ginsenosides, lanosterol and inotodiol.
Research output:
- Isolation, Physicochemical Characterization, and Biological Properties of Inotodiol, the Potent Pharmaceutical Oxysterol from Chaga Mushroom. Antioxidants 2023, 12(2), 447.
- Evaluation of Toxicity and Efficacy of Inotodiol asA an Anti-Inflammatory Agent Using Animal Model. Molecules 2022, 27(15), 4704.
- Variation of Triterpenic Acids in 12 Wild Syzygium formosum and Anti-Inflammation Activity on Human Keratinocyte HaCaT. Plants 2021, 10(11), 2428.
- Comparative Phytochemical Analysis of Syzygium formosum (Wall.) Masam Leaf and Its Biological Activities. Applied Sciences 2021, 11(22), 10552.
- Quantitative Analysis of Triterpenoids in the Cosmetic Products by LC/MS/MS. (Poster presentation during the 2022 Korean Society for Microbiology & Biotechnology's Spring Meeting & Interantional Symposium)
- Pharmacokinetics of inotodiol from Chaga mushroom after oral administration and direct infusion to abdominal cavity (Poster presentation during the 2021 Korean Society for Food Science and Technology's International Symposium & Annual Meeting)
- Identification of ginsenoside composition in Vietnamese ginseng (panax vietnamensis) by mass spectrometry. (Poster presentation during the 2019 Korean Society for Food Science and Technology's International Symposium & Annual Meeting)
